N-Acetylcysteine for Autism?
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Evaluating the Effectiveness of Adding N-acetylcysteine to the Risperidone Treatment Regimen in Patients With Autism Disorders
Introduction: Autism spectrum disorder (ASD) has been defined as a group of neurodevelopmental disorders with variable degrees of behavioral and mental problems. Although there is no definite treatment for ASD, antipsychotics are among the available treatments. Recent clinical trials are evaluating the effectiveness of combination therapy of antipsychotics and other drugs, including N-acetylcys...
متن کاملN-acetylcysteine for treatment of autism, a case report
There are a limited number of Food and Drug Administration (FDA)-approved medications for the treatment of autism. Meanwhile, oxidative stress and neuroinflammation are supposed to play a causative role in autism. N-acetylcysteine may provide cystine, a precursor for glutathione (GSH), which is an important antioxidant factor in the brain. We here report a child with autism, whose symptoms were...
متن کاملA randomized double blind placebo controlled clinical trial of N-Acetylcysteine added to risperidone for treating autistic disorders
BACKGROUND This study examined the efficacy and safety of N-acetylcysteine (NAC) augmentation for treating irritability in children and adolescents with autism spectrum disorders (ASD). METHOD Forty children and adolescents met diagnostic criteria for ASD according to DSM-IV. They were randomly allocated into one of the two groups of NAC (1200 mg/day)+risperidone or placebo+risperidone. NAC a...
متن کاملN-Acetylcysteine Compared to Metformin, Improves The Expression Profile of Growth Differentiation Factor-9 and Receptor Tyrosine Kinase c-Kit in The Oocytes of Patients with Polycystic Ovarian Syndrome
Objective Paracrine disruption of growth factors in women with polycystic ovarian syndrome results in production of low quality oocyte, especially following ovulation induction. The aim of this study was to investigate the effects of metformin (MET), N-acetylcysteine (NAC) and their combination on the hormonal levels and expression profile of GDF-9, BMP-15 and c-Kit, as hallmarks of oocyte qual...
متن کاملStudy of the Protective Effect of N-acetylcysteine on Testicular Tissue and Spermatogenesis Cells in Streptozotocin-diabetic Adult Rats
Background and aim: Diabetes affects the testicles by oxidative stress. The aim of this study was to investigate the protective effects of N-acetylcysteine on the number of spermatogenesis cells in diabetic rats. Materials and Methods: In this experimental study, 42 adult male Wistar rats were divided into 7 groups of 6. This study was carried out in two periods of 5 and 28 days. Thus, i...
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تاریخ انتشار 2017